Associations of mobile phone use with male semen quality and sex hormones / 环境与职业医学

Background Experimental studies have shown that radiofrequency electromagnetic waves emitted by mobile phones can cause adverse effects on male reproductive health, including decreased semen quality and altered sex hormones. However, the results of epidemiological studies on the relationship between mobile phone use and male semen quality are inconsistent. Furthermore, there are few epidemiological studies on the association of mobile phone use with sex hormones. Objective To explore the associations of mobile phone use with male semen quality and sex hormones. Methods A total of 2045 men visited the reproductive medicine center of a hospital in Wuhan and ordered infertility examination were recruited from December 2018 to January 2020. Information on mobile phone use was obtained using a questionnaire. Among them, 1232 and 1694 men were eligible for semen quality analyses and sex hormone analyses, respectively. Multiple linear and logistic regression models were used to analyze the associations of mobile phone use with male semen quality and sex hormones. Results After adjusting for potential confounders, there was no statistically significant associations of mobile phone use with sperm progressive motility, sperm total motility, sperm concentration, sperm count, or serum luteinizing hormone (P>0.05). However, serum total testosterone showed a declined tendency with increasing daily duration of mobile phone use (Ptrend=0.08). Compared with men with daily mobile phone use of 0-2 h, men with daily mobile phone use of 2.1-5, 5.1-8, and >8 h showed decreased serum total testosterone concentrations by 6.29% (95%CI: 0.40%-11.84%), 6.01% (95%CI: 0.60%-12.19%), and 7.87% (95%CI: 0.40%-14.79%), respectively. Conclusion Mobile phone use is not associated with male semen quality and serum luteinizing hormone, but increasing daily duration of mobile phone use is potentially associated with a tendency to lower male serum total testosterone.

Effects of exposure to disinfection byproducts on fetal growth and development: Research progress and perspectives / 环境与职业医学

Disinfection byproducts (DBPs) are a new class of contaminants that are formed during the process of drinking water disinfection in waterworks. To date, more than 700 DBPs have been identified in drinking water, many of which have been found to be potentially cytotoxic, genotoxic, carcinogenic, or teratogenic. As a class of ubiquitous contaminants with highly potential health hazards in drinking water, the reproductive and developmental toxicity of DBPs has been a public concern. This paper reviewed the research progress on the effects of exposure to DBPs on fetal growth and development and also proposed perspectives for future directions. This work aimed to provide reference for health risk assessment and standard establishment of DBPs in drinking water.

Investigation and analysis on the usage of mobile phone sports software in CDC staffs and its impact on their health / 中国职业医学

OBJECTIVE: To study the use of mobile phone sports software by the staffs of Centers for Disease Control( CDC)and its impact on their health. METHODS: Using cluster random sampling method,291 staff members of CDC in 7 prefecture-level cities in Hunan Province were selected as research subjects. The self-designed questionnaire was used to investigate the use of mobile phone sports software,and the Sub-Health Scale was used to investigate their health status.The impact of mobile phone sports software on their health was analyzed. RESULTS: The usage rate of mobile phone sports software was 28. 5%(83/291). The utilization rate of mobile phone sports software in postgraduate staffs was higher than that of undergraduates,college graduates and those with less than bachelor's degree( P < 0. 01). The usage rate of mobile exercise software of the CDC staff whose BMI was 18. 5 ~ kg/m~2 was lower than those whose BMI was 24. 0 ~ or 28. 0 ~kg/m~2(P < 0. 001). The sub-health incidence rate in those who used mobile sports software was lower than those who did not( P < 0. 05). The incidences of feeling fatigue,dizziness,lack of attention,upset,more dream,insomnia,poor memory in CDC staffs who used mobile phone sports software were lower than those who did not( P < 0. 05). CONCLUSION: The use of mobile phone sports software has positive effect on health promotion in CDC staffs.

Practice of evidence based nursing program in rehabilitation nursing of ischemic stroke / 现代临床护理

Objective To explore the clinical effect of evidence-based nursing program in rehabilitation nursing of ischemic stroke. Methods Eighty-four patients with ischemic stroke admitted in our department from February 2015 to November 2016 were randomly divided into study group and control group(n=42).The evidence-based nursing program was adopted in the study group and in the control group conventional nursing program was used.In 6 months follow-up,the two groups were compared concerning compliance and daily life ability and hand function. Results The scores on rehabilitation training,life and rest,follow-up visits and the total score of compliance in the study group were significantly higher than those of the control group after 6 months follow-up(P<0.05).The Barthel index(BI)index of the study group was significantly higher than that of the control group,and the score on the nine-hole column was significantly lower than that of the control group(P<0.05). Conclusion Evidence-based nursing can effectively improve the compliance of patients with ischemic stroke and daily life ability and hand function after discharge,so it is worthy of clinical application.

Controlled study of serum cytokines and high-sensitive C-reactive protein in the post-stroke depression and depression patients / 中华行为医学与脑科学杂志

Objective To compare the serum cytokines and high-sensitive C-reactive protein (hs-CRP) in the post-stroke depression(PSD) and depression patients,and further study of the pathogenesis PSD and depression.Methods The levels of serum IL-1β,IL-6 and TNF-α in the PSD group(n=30),the depression group(n=30),the post-stroke non-depression group(n=30)and normal control group(n=30)were measured with enzymatic-linked immunosorbent assay(ELISA),and the levels of serum hs-CRP were measured by scatter rate nephelometryat for these four groups.Results The levels of serum IL-1β,IL-6,TNF-α and hs-CRP in the PSD group,the depression group,the the post-stroke non-depression group and the normal control group were respectively((137.23 ±8.12) pg/ml,(34.12±3.12) pg/ml,(64.62±6.11) pg/ml,(15.36±6.25) mg/L) ; ((133.21 ±7.56) pg/ml,(33.56±2.65) pg/ml,(62.95±5.66) pg/ml,(4.02± 1.21) mg/L) ; ((43.25 ±6.23) pg/ml,(16.12±2.60) pg/ml,(32.23±7.12) pg/ml,(14.88±7.23) mg/L) ; ((42.12±5.78) pg/ml,(15.32±3.23) pg/ml,(31.55±6.70) pg/ml,(3.68± 1.11)mg/L).The levels of serum IL-1β,IL-6 and TNF-αt in the PSD group and the depression group increased significantly than those in the the post-stroke non-depression group and the normal control group(P＜0.01).The levels of serum hs-CRP:PSD group ＞ post-stroke non-depression group ＞ depression group ＞ normal control group(P＜0.05).Conclusion The PSD and depression may have the same immune mechanism.

Curative effect and safety of percutaneous closure of patent foramen ovale on 23 migraineurs / 中华神经科杂志

Objective To evaluate the clinical effect and safety of percutaneous closure of patent foramen ovalein treatment of migraine.Methods We studied 23 patients with migraine who were tested positive in Contrast Transcranial Doppler (TCDc) at the Department of Neurology in Bethune First Hospital of Jilin University between 2010 May and 2011 November.Procedures of transcatheterclosure of patent foramen ovale were performed at Department of Cardiovascular Surgery.At varied time points post-surgery,the patients were re-examined by TCDc and transthoracic echocardiograph (TTE) and followed up by phone interviewed with Headache Impact Test-6 (HIT-6) questionnaire to elevate improvement of migraine.The data was analyzed statistically.Results Percutaneous closure was successful in all patients without major long-term side-effects.At follow-ups at 48-542 days ((247 ± 145) days) post-surgery,the scores of HIT-6 were reduced to 38-70 (51 ± 9),compared to the pre-operative scores of 42-76 (61 ± 8).Disability by migraine had significantly improved (t =4.80,P ＜ 0.05).In 6 patients with migraine with aura,the scores of HIT-6 were reduced to 46-56 (51 ± 3),from preoperative scores of 63-76 (69 ± 4) and their disability affected by migraine had significantly improved (t =6.80,P ＜0.05).In 17 patients with migraine without aura,the scores of HIT-6 after surgery were reduced to 36-70 (52-10) from the preoperative scores of 42-69 (60 ± 8) and disability affected by migraine in this group had significantly improved (t =3.77,P ＜0.05).Among 18 patients having MRI or CT examination before the operation,8 patients had neurological events (such as cerebral infarction,cerebral ischemia) with average age of (44 ± 7) years old.In this group,disability affected by migraine had significantly improved (the HIT-6 scores:49 ± 7 vs 58 ± 10,t =2.49,P ＜ 0.05).Conclusion Percutaneous closure of PFO showed significant improvement in migraine treatment and it is a safe procedure.